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» A Comparative Study of Industrial Static Analysis Tools
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77
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BMCBI
2007
145views more  BMCBI 2007»
14 years 10 months ago
Genome bioinformatic analysis of nonsynonymous SNPs
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...
SIAMFM
2011
75views more  SIAMFM 2011»
14 years 1 months ago
Dynamic Hedging of Portfolio Credit Derivatives
As shown by the recent turmoil in credit markets, much remains to be done for the proper risk management of credit derivatives. In particular, the static copula-based models commo...
Rama Cont, Yu Hang Kan
93
Voted
BMCBI
2010
131views more  BMCBI 2010»
14 years 10 months ago
A comparison of approximation techniques for variance-based sensitivity analysis of biochemical reaction systems
Background: Sensitivity analysis is an indispensable tool for the analysis of complex systems. In a recent paper, we have introduced a thermodynamically consistent variance-based ...
Hong-Xuan Zhang, John Goutsias
77
Voted
BMCBI
2010
118views more  BMCBI 2010»
14 years 10 months ago
Testing for mean and correlation changes in microarray experiments: an application for pathway analysis
Background: Microarray experiments examine the change in transcript levels of tens of thousands of genes simultaneously. To derive meaningful data, biologists investigate the resp...
Mayer Alvo, Zhongzhu Liu, Andrew Williams, Carole ...
83
Voted
BMCBI
2010
135views more  BMCBI 2010»
14 years 10 months ago
Lists2Networks: Integrated analysis of gene/protein lists
Background: Systems biologists are faced with the difficultly of analyzing results from large-scale studies that profile the activity of many genes, RNAs and proteins, applied in ...
Alexander Lachmann, Avi Ma'ayan