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CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 4 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
CGF
2008
142views more  CGF 2008»
14 years 11 months ago
Visualizing Genome Expression and Regulatory Network Dynamics in Genomic and Metabolic Context
DNA microarrays are used to measure the expression levels of thousands of genes simultaneously. In a time series experiment, the gene expressions are measured as a function of tim...
Michel A. Westenberg, Sacha A. F. T. van Hijum, Os...
88
Voted
BMCBI
2006
118views more  BMCBI 2006»
14 years 11 months ago
Low degree metabolites explain essential reactions and enhance modularity in biological networks
Background: Recently there has been a lot of interest in identifying modules at the level of genetic and metabolic networks of organisms, as well as in identifying single genes an...
Areejit Samal, Shalini Singh, Varun Giri, Sandeep ...
BMCBI
2011
14 years 3 months ago
Reconstructing genome-wide regulatory network of E. coli using transcriptome data and predicted transcription factor activities
Background: Gene regulatory networks play essential roles in living organisms to control growth, keep internal metabolism running and respond to external environmental changes. Un...
Yao Fu, Laura R. Jarboe, Julie A. Dickerson
95
Voted
NIPS
2004
15 years 1 months ago
Supervised Graph Inference
We formulate the problem of graph inference where part of the graph is known as a supervised learning problem, and propose an algorithm to solve it. The method involves the learni...
Jean-Philippe Vert, Yoshihiro Yamanishi