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BMCBI
2006
108views more  BMCBI 2006»
14 years 9 months ago
A new pooling strategy for high-throughput screening: the Shifted Transversal Design
Background: In binary high-throughput screening projects where the goal is the identification of low-frequency events, beyond the obvious issue of efficiency, false positives and ...
Nicolas Thierry-Mieg
BMCBI
2006
95views more  BMCBI 2006»
14 years 9 months ago
Estimate haplotype frequencies in pedigrees
Background: Haplotype analysis has gained increasing attention in the context of association studies of disease genes and drug responsivities over the last years. The potential us...
Qiangfeng Zhang, YuZhong Zhao, Guoliang Chen, Yun ...
BMCBI
2006
144views more  BMCBI 2006»
14 years 9 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
CONSTRAINTS
2006
99views more  CONSTRAINTS 2006»
14 years 9 months ago
An Integrated Method for Planning and Scheduling to Minimize Tardiness
We combine mixed integer linear programming (MILP) and constraint programming (CP) to minimize tardiness in planning and scheduling. Tasks are allocated to facilities using MILP an...
John N. Hooker
ENTCS
2006
138views more  ENTCS 2006»
14 years 9 months ago
Variables as Resource in Separation Logic
Separation logic [20,21,14] began life as an extended formalisation of Burstall's treatment of list-mutating programs [8]. It rapidly became clear that there was more that it...
Richard Bornat, Cristiano Calcagno, Hongseok Yang