In sequencing by hybridization (SBH), one has to reconstruct a sequence from its l-long substrings. SBH was proposed as an alternative to gel-based DNA sequencing approaches, but ...
Amir Ben-Dor, Itsik Pe'er, Ron Shamir, Roded Shara...
Abstract. Haplotype inference from genotype data is a key computational problem in bioinformatics, since retrieving directly haplotype information from DNA samples is not feasible ...
We study the complexity of the Accretive Graph Assembly Problem (AGAP). An instance of AGAP consists of an edge-weighted graph G, a seed vertex in G, and a temperature . The goal i...
DNA sequencing by hybridization (SBH) induces errors in the biochemical experiment. Some of them are random and disappear when the experiment is repeated. Others are systematic, i...
Jacek Blazewicz, Fred Glover, Marta Kasprzak, Wojc...
A central question in computational biology is the design of genetic markers to distinguish between two given sets of (DNA) sequences. This question is formalized as the NP-comple...