We discuss the problem of optimally "finishing" a partially sequenced, reconstructed DNA segment. At first sight, this appears to be computationally hard. We construct a...
: Deoxyribonucleic Acid or DNA-based computing is an emerging field that bridging the gap between chemistry, molecular biology, computer science, and mathematics. This research are...
L. M. Adleman launched the field of DNA computing with a demonstration in 1994 that strands of DNA could be used to solve the Hamiltonian path problem for a simple graph. He also...
We present an original approach to identifying sequence variants in a mixed DNA population from sequence trace data. The heart of the method is based on parsimony: given a wildtyp...
Previously, we described ways to implement the functions AND and OR in a DNA computer consisting of microreactors with attached heating elements that control annealing of DNA. Base...
Michael S. Livstone, Ron Weiss, Laura F. Landweber