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» A Data Model for Effectively Computable Functions
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BMCBI
2010
135views more  BMCBI 2010»
14 years 10 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...
BMCBI
2006
94views more  BMCBI 2006»
14 years 10 months ago
Simulation of microarray data with realistic characteristics
Background: Microarray technologies have become common tools in biological research. As a result, a need for effective computational methods for data analysis has emerged. Numerou...
Matti Nykter, Tommi Aho, Miika Ahdesmäki, Pek...
JCB
2007
130views more  JCB 2007»
14 years 10 months ago
Bayesian Inference of MicroRNA Targets from Sequence and Expression Data
MicroRNAs (miRNAs) regulate a large proportion of mammalian genes by hybridizing to targeted messenger RNAs (mRNAs) and down-regulating their translation into protein. Although mu...
Jim C. Huang, Quaid Morris, Brendan J. Frey
TCAD
2008
114views more  TCAD 2008»
14 years 10 months ago
Test-Quality/Cost Optimization Using Output-Deviation-Based Reordering of Test Patterns
At-speed functional testing, delay testing, and n-detection test sets are being used today to detect deep submicrometer defects. However, the resulting test data volumes are too hi...
Zhanglei Wang, Krishnendu Chakrabarty
PAMI
2011
14 years 5 months ago
Approximately Global Optimization for Robust Alignment of Generalized Shapes
—In this paper, we introduce a novel method to solve shape alignment problems. We use gray-scale “images” to represent source shapes, and propose a novel two-component Gaussi...
Hongsheng Li, Tian Shen, Xiaolei Huang