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BMCBI
2006
120views more  BMCBI 2006»
15 years 4 months ago
Optimizing amino acid substitution matrices with a local alignment kernel
Background: Detecting remote homologies by direct comparison of protein sequences remains a challenging task. We had previously developed a similarity score between sequences, cal...
Hiroto Saigo, Jean-Philippe Vert, Tatsuya Akutsu
BMCBI
2006
147views more  BMCBI 2006»
15 years 4 months ago
QPath: a method for querying pathways in a protein-protein interaction network
Background: Sequence comparison is one of the most prominent tools in biological research, and is instrumental in studying gene function and evolution. The rapid development of hi...
Tomer Shlomi, Daniel Segal, Eytan Ruppin, Roded Sh...
BMCBI
2006
118views more  BMCBI 2006»
15 years 4 months ago
Djinn Lite: a tool for customised gene transcript modelling, annotation-data enrichment and exploration
Background: There is an ever increasing rate of data made available on genetic variation, transcriptomes and proteomes. Similarly, a growing variety of bioinformatic programs are ...
Erdahl T. Teber, Edward Crawford, Kent B. Bolton, ...
BMCBI
2006
120views more  BMCBI 2006»
15 years 4 months ago
Classification of protein quaternary structure by functional domain composition
Background: The number and the arrangement of subunits that form a protein are referred to as quaternary structure. Quaternary structure is an important protein attribute that is ...
Xiaojing Yu, Chuan Wang, Yixue Li
BMCBI
2007
141views more  BMCBI 2007»
15 years 4 months ago
Using structural motif descriptors for sequence-based binding site prediction
Background: Many protein sequences are still poorly annotated. Functional characterization of a protein is often improved by the identification of its interaction partners. Here, ...
Andreas Henschel, Christof Winter, Wan Kyu Kim, Mi...