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BMCBI
2008
148views more  BMCBI 2008»
14 years 10 months ago
Critical assessment of alignment procedures for LC-MS proteomics and metabolomics measurements
Background: Liquid chromatography coupled to mass spectrometry (LC-MS) has become a prominent tool for the analysis of complex proteomics and metabolomics samples. In many applica...
Eva Lange, Ralf Tautenhahn, Steffen Neumann, Cleme...
BMCBI
2006
139views more  BMCBI 2006»
14 years 10 months ago
Improvement in accuracy of multiple sequence alignment using novel group-to-group sequence alignment algorithm with piecewise li
Background: Multiple sequence alignment (MSA) is a useful tool in bioinformatics. Although many MSA algorithms have been developed, there is still room for improvement in accuracy...
Shinsuke Yamada, Osamu Gotoh, Hayato Yamana
ESWA
2006
195views more  ESWA 2006»
14 years 10 months ago
JavaDON: an open-source expert system shell
The paper describes JavaDON, an open-source expert systems shell based on the OBOA framework for developing intelligent systems. The central idea of the JavaDON project was to mak...
Bojan Tomic, Jelena Jovanovic, Vladan Devedzic
BMCBI
2005
85views more  BMCBI 2005»
14 years 9 months ago
Processing methods for differential analysis of LC/MS profile data
Background: Liquid chromatography coupled to mass spectrometry (LC/MS) has been widely used in proteomics and metabolomics research. In this context, the technology has been incre...
Mikko Katajamaa, Matej Oresic
BMCBI
2005
156views more  BMCBI 2005»
14 years 9 months ago
A new dynamical layout algorithm for complex biochemical reaction networks
Background: To study complex biochemical reaction networks in living cells researchers more and more rely on databases and computational methods. In order to facilitate computatio...
Katja Wegner, Ursula Kummer