Sciweavers

7168 search results - page 1233 / 1434
» A Factorization Approach to Grouping
Sort
View
WM
2003
15 years 7 months ago
Knowledge discovery methods
: Coping with complex and dynamic environments forces companies to invest in the resource knowledge for the maintenance of their operational reliability; they have to create and to...
Stefan Smolnik
BIODATAMINING
2008
130views more  BIODATAMINING 2008»
15 years 6 months ago
Uncovering mechanisms of transcriptional regulations by systematic mining of cis regulatory elements with gene expression profil
Background: Contrary to the traditional biology approach, where the expression patterns of a handful of genes are studied at a time, microarray experiments enable biologists to st...
Qicheng Ma, Gung-Wei Chirn, Joseph D. Szustakowski...
BMCBI
2010
116views more  BMCBI 2010»
15 years 6 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
BMCBI
2010
135views more  BMCBI 2010»
15 years 6 months ago
Quadratic variance models for adaptively preprocessing SELDI-TOF mass spectrometry data
Background: Surface enhanced laser desorption/ionization time-of-flight mass spectrometry (SELDI) is a proteomics tool for biomarker discovery and other high throughput applicatio...
Vincent A. Emanuele II, Brian M. Gurbaxani
BMCBI
2008
103views more  BMCBI 2008»
15 years 6 months ago
Parameter estimation for robust HMM analysis of ChIP-chip data
Background: Tiling arrays are an important tool for the study of transcriptional activity, proteinDNA interactions and chromatin structure on a genome-wide scale at high resolutio...
Peter Humburg, David Bulger, Glenn Stone
« Prev « First page 1233 / 1434 Last » Next »