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BMCBI
2010
160views more  BMCBI 2010»
14 years 10 months ago
Quantitative model for inferring dynamic regulation of the tumour suppressor gene p53
Background: The availability of various "omics" datasets creates a prospect of performing the study of genomewide genetic regulatory networks. However, one of the major ...
Junbai Wang, Tianhai Tian
BMCBI
2010
162views more  BMCBI 2010»
14 years 10 months ago
Moara: a Java library for extracting and normalizing gene and protein mentions
Background: Gene/protein recognition and normalization are important preliminary steps for many biological text mining tasks, such as information retrieval, protein-protein intera...
Mariana L. Neves, José María Carazo,...
BMCBI
2010
125views more  BMCBI 2010»
14 years 10 months ago
Haplotype allelic classes for detecting ongoing positive selection
Background: Natural selection eliminates detrimental and favors advantageous phenotypes. This process leaves characteristic signatures in underlying genomic segments that can be r...
Julie Hussin, Philippe Nadeau, Jean-Françoi...
BMCBI
2010
139views more  BMCBI 2010»
14 years 10 months ago
A highly efficient multi-core algorithm for clustering extremely large datasets
Background: In recent years, the demand for computational power in computational biology has increased due to rapidly growing data sets from microarray and other high-throughput t...
Johann M. Kraus, Hans A. Kestler
BMCBI
2010
110views more  BMCBI 2010»
14 years 10 months ago
Towards the systematic discovery of signal transduction networks using phosphorylation dynamics data
Background: Phosphorylation is a ubiquitous and fundamental regulatory mechanism that controls signal transduction in living cells. The number of identified phosphoproteins and th...
Haruna Imamura, Nozomu Yachie, Rintaro Saito, Yasu...
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