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BMCBI
2010
127views more  BMCBI 2010»
14 years 10 months ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
BMCBI
2010
135views more  BMCBI 2010»
14 years 10 months ago
Efficient genome-scale phylogenetic analysis under the duplication-loss and deep coalescence cost models
Background: Genomic data provide a wealth of new information for phylogenetic analysis. Yet making use of this data requires phylogenetic methods that can efficiently analyze extr...
Mukul S. Bansal, J. Gordon Burleigh, Oliver Eulens...
BMCBI
2010
104views more  BMCBI 2010»
14 years 10 months ago
Formal reasoning on qualitative models of coinfection of HIV and Tuberculosis and HAART therapy
Background: Several diseases, many of which nowadays pandemic, consist of multifactorial pathologies. Paradigmatic examples come from the immune response to pathogens, in which ca...
Anil Sorathiya, Andrea Bracciali, Pietro Liò...
BMCBI
2010
112views more  BMCBI 2010»
14 years 10 months ago
Knowledge-based analysis of microarrays for the discovery of transcriptional regulation relationships
Background: The large amount of high-throughput genomic data has facilitated the discovery of the regulatory relationships between transcription factors and their target genes. Wh...
Junhee Seok, Amit Kaushal, Ronald W. Davis, Wenzho...
BMCBI
2007
128views more  BMCBI 2007»
14 years 10 months ago
Absolute estimation of initial concentrations of amplicon in a real-time RT-PCR process
Background: Since real time PCR was first developed, several approaches to estimating the initial quantity of template in an RT-PCR reaction have been tried. While initially only ...
Marjo V. Smith, Chris R. Miller, Michael Kohn, Nig...
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