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152
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BMCBI
2011
14 years 7 months ago
ASPDock: protein-protein docking algorithm using atomic solvation parameters model
Background: Atomic Solvation Parameters (ASP) model has been proven to be a very successful method of calculating the binding free energy of protein complexes. This suggests that ...
Lin Li, Dachuan Guo, Yangyu Huang, Shiyong Liu, Yi...
116
Voted
RECOMB
2005
Springer
16 years 1 months ago
Information Theoretic Approaches to Whole Genome Phylogenies
We describe a novel method for efficient reconstruction of phylogenetic trees, based on sequences of whole genomes or proteomes, whose lengths may greatly vary. The core of our me...
David Burstein, Igor Ulitsky, Tamir Tuller, Benny ...
99
Voted
ICCAD
2001
IEEE
192views Hardware» more  ICCAD 2001»
15 years 9 months ago
BOOM - A Heuristic Boolean Minimizer
We present a two-level Boolean minimization tool (BOOM) based on a new implicant generation paradigm. In contrast to all previous minimization methods, where the implicants are ge...
Jan Hlavicka, Petr Fiser
BIBM
2009
IEEE
206views Bioinformatics» more  BIBM 2009»
15 years 7 months ago
Application of Kernel Functions for Accurate Similarity Search in Large Chemical Databases
Background: Similaritysearch in chemical structure databases is an important problem with many applications in chemical genomics, drug design, and efficient chemical probe screeni...
Xiaohong Wang, Jun Huan, Aaron M. Smalter, Gerald ...
112
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BIBE
2007
IEEE
127views Bioinformatics» more  BIBE 2007»
15 years 7 months ago
A Heuristic for Phylogenetic Reconstruction Using Transposition
Abstract—Because of the advent of high-throughput sequencing and the consequent reduction in cost of sequencing, many organisms have been completely sequenced and most of their g...
Feng Yue, Meng Zhang, Jijun Tang