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» A Flexible Algorithm for Pairwise Protein Structure Alignmen...
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BMCBI
2010
139views more  BMCBI 2010»
14 years 9 months ago
CMASA: an accurate algorithm for detecting local protein structural similarity and its application to enzyme catalytic site anno
Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
Gong-Hua Li, Jing-Fei Huang
BMCBI
2007
156views more  BMCBI 2007»
14 years 9 months ago
Accuracy of structure-based sequence alignment of automatic methods
Background: Accurate sequence alignments are essential for homology searches and for building three-dimensional structural models of proteins. Since structure is better conserved ...
Changhoon Kim, Byungkook Lee
RECOMB
2002
Springer
15 years 9 months ago
Revealing protein structures: a new method for mapping antibody epitopes
A recent idea for determining the three-dimensional structure of a protein uses antibody recognition of surface structure and random peptide libraries to map antibody epitope comb...
Brendan Mumey, Brian W. Bailey, Edward A. Dratz
95
Voted
BMCBI
2010
139views more  BMCBI 2010»
14 years 9 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
BMCBI
2006
129views more  BMCBI 2006»
14 years 9 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...