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BMCBI
2005
125views more  BMCBI 2005»
14 years 9 months ago
DIALIGN-T: An improved algorithm for segment-based multiple sequence alignment
Background: We present a complete re-implementation of the segment-based approach to multiple protein alignment that contains a number of improvements compared to the previous ver...
Amarendran R. Subramanian, Jan Weyer-Menkhoff, Mic...
74
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GECCO
2006
Springer
130views Optimization» more  GECCO 2006»
15 years 1 months ago
Pairwise sequence comparison for fitness evaluation in evolutionary structural software testing
Evolutionary algorithms are among the metaheuristic search methods that have been applied to the structural test data generation problem. Fitness evaluation methods play an import...
H. Turgut Uyar, A. Sima Etaner-Uyar, A. Emre Harma...
ARC
2007
Springer
123views Hardware» more  ARC 2007»
15 years 1 months ago
Multiple Sequence Alignment Using Reconfigurable Computing
The alignment of multiple protein (or DNA) sequences is a current problem in Bioinformatics. ClustalW is the most popular heuristic algorithm for multiple sequence alignment. Pairw...
Carlos R. Erig Lima, Heitor S. Lopes, Maiko R. Mor...
BIBE
2008
IEEE
142views Bioinformatics» more  BIBE 2008»
15 years 4 months ago
Optimizing performance, cost, and sensitivity in pairwise sequence search on a cluster of PlayStations
— The Smith-Waterman algorithm is a dynamic programming method for determining optimal local alignments between nucleotide or protein sequences. However, it suffers from quadrati...
Ashwin M. Aji, Wu-chun Feng
BMCBI
2010
163views more  BMCBI 2010»
14 years 9 months ago
Reduced representation of protein structure: implications on efficiency and scope of detection of structural similarity
Background: Computational comparison of two protein structures is the starting point of many methods that build on existing knowledge, such as structure modeling (including modeli...
Zong Hong Zhang, Hwee Kuan Lee, Ivana Mihalek