Background: Although homology-based methods are among the most widely used methods for predicting the structure and function of proteins, the question as to whether interface sequ...
We develop an integrated probabilistic model to combine protein physical interactions, genetic interactions, highly correlated gene expression network, protein complex data, and d...
Pairwise sequence alignment is a fundamental operation for homology search in bioinformatics. For two DNA or protein sequences of length ¢ and £ , full-matrix (FM), dynamic prog...
Adrian Driga, Paul Lu, Jonathan Schaeffer, Duane S...
X-ray crystallography is currently the most common way protein structures are elucidated. One of the most time-consuming steps in the crystallographic process is interpretation of...
Background: The chemical property and biological function of a protein is a direct consequence of its primary structure. Several algorithms have been developed which determine ali...
Kshitiz Gupta, Dina Thomas, S. V. Vidya, K. V. Ven...