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WABI
2005
Springer
120views Bioinformatics» more  WABI 2005»
15 years 5 months ago
Multiple Structural RNA Alignment with Lagrangian Relaxation
In contrast to proteins, many classes of functionally related RNA molecules show a rather weak sequence conservation but instead a fairly well conserved secondary structure. Hence ...
Markus Bauer, Gunnar W. Klau, Knut Reinert
BMCBI
2004
126views more  BMCBI 2004»
14 years 11 months ago
A probabilistic model for the evolution of RNA structure
Background: For the purposes of finding and aligning noncoding RNA gene- and cis-regulatory elements in multiple-genome datasets, it is useful to be able to derive multi-sequence ...
Ian Holmes
CAIP
2009
Springer
155views Image Analysis» more  CAIP 2009»
15 years 6 months ago
Algorithms for the Sample Mean of Graphs
Measures of central tendency for graphs are important for protoype construction, frequent substructure mining, and multiple alignment of protein structures. This contribution propo...
Brijnesh J. Jain, Klaus Obermayer
BMCBI
2007
117views more  BMCBI 2007»
14 years 12 months ago
Supervised multivariate analysis of sequence groups to identify specificity determining residues
Background: Proteins that evolve from a common ancestor can change functionality over time, and it is important to be able identify residues that cause this change. In this paper ...
Iain M. Wallace, Desmond G. Higgins
IPPS
2009
IEEE
15 years 6 months ago
Parallel reconstruction of neighbor-joining trees for large multiple sequence alignments using CUDA
Computing large multiple protein sequence alignments using progressive alignment tools such as ClustalW requires several hours on state-of-the-art workstations. ClustalW uses a th...
Yongchao Liu, Bertil Schmidt, Douglas L. Maskell