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BMCBI
2010
147views more  BMCBI 2010»
14 years 9 months ago
baySeq: Empirical Bayesian methods for identifying differential expression in sequence count data
Background: High throughput sequencing has become an important technology for studying expression levels in many types of genomic, and particularly transcriptomic, data. One key w...
Thomas J. Hardcastle, Krystyna A. Kelly
BMCBI
2008
132views more  BMCBI 2008»
14 years 9 months ago
The Average Mutual Information Profile as a Genomic Signature
Background: Occult organizational structures in DNA sequences may hold the key to understanding functional and evolutionary aspects of the DNA molecule. Such structures can also p...
Mark Bauer, Sheldon M. Schuster, Khalid Sayood
BMCBI
2008
124views more  BMCBI 2008»
14 years 9 months ago
A probe-treatment-reference (PTR) model for the analysis of oligonucleotide expression microarrays
Background: Microarray pre-processing usually consists of normalization and summarization. Normalization aims to remove non-biological variations across different arrays. The norm...
Huanying Ge, Chao Cheng, Lei M. Li
BMCBI
2008
148views more  BMCBI 2008»
14 years 9 months ago
Discovering biclusters in gene expression data based on high-dimensional linear geometries
Background: In DNA microarray experiments, discovering groups of genes that share similar transcriptional characteristics is instrumental in functional annotation, tissue classifi...
Xiangchao Gan, Alan Wee-Chung Liew, Hong Yan
CCR
2008
91views more  CCR 2008»
14 years 9 months ago
Serial experiments online
Current network protocols must comply with rigid interfaces and rules of behavior to fit into well defined, vertical protocol stacks. It is difficult for network designers to offe...
Juan J. Ramos-Muñoz, Lidia Yamamoto, Christ...