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» A Framework for Modeling DNA Based Molecular Systems
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BMCBI
2007
147views more  BMCBI 2007»
14 years 9 months ago
Comparative analysis of long DNA sequences by per element information content using different contexts
Background: Features of a DNA sequence can be found by compressing the sequence under a suitable model; good compression implies low information content. Good DNA compression mode...
Trevor I. Dix, David R. Powell, Lloyd Allison, Jul...
75
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GECCO
2004
Springer
150views Optimization» more  GECCO 2004»
15 years 2 months ago
Systems Biology Modeling in Human Genetics Using Petri Nets and Grammatical Evolution
Understanding the hierarchical relationships among biochemical, metabolic, and physiological systems in the mapping between genotype and phenotype is expected to improve the diagno...
Jason H. Moore, Lance W. Hahn
80
Voted
CPHYSICS
2007
84views more  CPHYSICS 2007»
14 years 9 months ago
Simulating botulinum neurotoxin with constant pH molecular dynamics in Generalized Born implicit solvent
A new method was proposed by Mongan et al for constant pH molecular dynamics simulation and was implemented in AMBER 8 package. Protonation states are modeled with different char...
Yongzhi Chen, Xin Chen, Yuefan Deng
BIOSYSTEMS
2008
129views more  BIOSYSTEMS 2008»
14 years 9 months ago
Reconstruction of DNA sequences using genetic algorithms and cellular automata: Towards mutation prediction?
Change of DNA sequence that fuels evolution is, to a certain extent, a deterministic process because mutagenesis does not occur in an absolutely random manner. So far, it has not ...
Ch. Mizas, Georgios Ch. Sirakoulis, Vasilios A. Ma...
ISMB
1998
14 years 10 months ago
BioSim: A New Qualitative Simulation Environment for Molecular Biology
Traditionally, biochemical systems are modelled usingkinetics anddifferential equationsin a quantitative simulator. However,for manybiological processes detailed quantitative info...
Karsten R. Heidtke, Steffen Schulze-Kremer