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» A Framework for Molecular Biology Data Integration
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BMCBI
2008
202views more  BMCBI 2008»
14 years 9 months ago
Network motif-based identification of transcription factor-target gene relationships by integrating multi-source biological data
Background: Integrating data from multiple global assays and curated databases is essential to understand the spatiotemporal interactions within cells. Different experiments measu...
Yuji Zhang, Jianhua Xuan, Benildo de los Reyes, Ro...
BMCBI
2010
135views more  BMCBI 2010»
14 years 9 months ago
Integration and visualization of systems biology data in context of the genome
Background: High-density tiling arrays and new sequencing technologies are generating rapidly increasing volumes of transcriptome and protein-DNA interaction data. Visualization a...
J. Christopher Bare, Tie Koide, David J. Reiss, Da...
BICOB
2010
Springer
14 years 9 months ago
Integrative Biomarker Discovery for Breast Cancer Metastasis from Gene Expression and Protein Interaction Data Using Error-toler
Biomarker discovery for complex diseases is a challenging problem. Most of the existing approaches identify individual genes as disease markers, thereby missing the interactions a...
Rohit Gupta, Smita Agrawal, Navneet Rao, Ze Tian, ...
BMCBI
2006
174views more  BMCBI 2006»
14 years 9 months ago
Genome wide prediction of protein function via a generic knowledge discovery approach based on evidence integration
Background: The automation of many common molecular biology techniques has resulted in the accumulation of vast quantities of experimental data. One of the major challenges now fa...
Jianghui Xiong, Simon Rayner, Kunyi Luo, Yinghui L...
WOB
2004
14 years 11 months ago
An Integrated Model for Cellular Analysis
ABSTRACT. We present the MOlecular NETwork (MONET) ontology as a model to integrate data from different networks that govern cell function. To achieve this, different existing onto...
Eduardo Battistella, José Souza, Clá...