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BMCBI
2006
104views more  BMCBI 2006»
13 years 6 months ago
MANET: tracing evolution of protein architecture in metabolic networks
Background: Cellular metabolism can be characterized by networks of enzymatic reactions and transport processes capable of supporting cellular life. Our aim is to find evolutionar...
Hee Shin Kim, Jay E. Mittenthal, Gustavo Caetano-A...
BMCBI
2002
129views more  BMCBI 2002»
13 years 6 months ago
SeqHound: biological sequence and structure database as a platform for bioinformatics research
Background: SeqHound has been developed as an integrated biological sequence, taxonomy, annotation and 3-D structure database system. It provides a high-performance server platfor...
Katerina Michalickova, Gary D. Bader, Michel Dumon...
CGF
2008
151views more  CGF 2008»
13 years 5 months ago
Navigation and Exploration of Interconnected Pathways
Visualizing pathways, i. e. models of cellular functional networks, is a challenging task in computer assisted biomedicine. Pathways are represented as large collections of interw...
Marc Streit, Michael Kalkusch, Karl Kashofer, Diet...
BMCBI
2007
121views more  BMCBI 2007»
13 years 6 months ago
A procedure for identifying homologous alternative splicing events
Background: The study of the functional role of alternative splice isoforms of a gene is a very active area of research in biology. The difficulty of the experimental approach (in...
David Talavera, Adam Hospital, Modesto Orozco, Xav...
BMCBI
2010
191views more  BMCBI 2010»
13 years 6 months ago
BiGG: a Biochemical Genetic and Genomic knowledgebase of large scale metabolic reconstructions
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...