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» A Functional Ontology of Observation and Measurement
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BMCBI
2010
121views more  BMCBI 2010»
14 years 11 months ago
Knowledge-based annotation of small molecule binding sites in proteins
Background: The study of protein-small molecule interactions is vital for understanding protein function and for practical applications in drug discovery. To benefit from the rapi...
Ratna R. Thangudu, Manoj Tyagi, Benjamin A. Shoema...
BMCBI
2008
135views more  BMCBI 2008»
14 years 11 months ago
Inferring the role of transcription factors in regulatory networks
Background: Expression profiles obtained from multiple perturbation experiments are increasingly used to reconstruct transcriptional regulatory networks, from well studied, simple...
Philippe Veber, Carito Guziolowski, Michel Le Borg...
BMCBI
2007
128views more  BMCBI 2007»
14 years 11 months ago
A Bayesian nonparametric method for prediction in EST analysis
Background: Expressed sequence tags (ESTs) analyses are a fundamental tool for gene identification in organisms. Given a preliminary EST sample from a certain library, several sta...
Antonio Lijoi, Ramsés H. Mena, Igor Prü...
BMCBI
2007
102views more  BMCBI 2007»
14 years 11 months ago
Multivariate Analysis and Visualization of Splicing Correlations in Single-Gene Transcriptomes
Background: RNA metabolism, through 'combinatorial splicing', can generate enormous structural diversity in the proteome. Alternative domains may interact, however, with...
Mark C. Emerick, Giovanni Parmigiani, William S. A...
EOR
2010
110views more  EOR 2010»
14 years 11 months ago
Pricing surplus server capacity for mean waiting time sensitive customers
Resources including various assets of supply chains, face random demand over time and can be shared by others. We consider an operational setting where a resource is shared by two...
Sudhir K. Sinha, N. Rangaraj, N. Hemachandra