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BMCBI
2008
242views more  BMCBI 2008»
14 years 12 months ago
New time-scale criteria for model simplification of bio-reaction systems
Background: Quasi-steady state approximation (QSSA) based on time-scale analysis is known to be an effective method for simplifying metabolic reaction system, but the conventional...
Junwon Choi, Kyung-won Yang, Tai-yong Lee, Sang Yu...
BMCBI
2008
102views more  BMCBI 2008»
14 years 12 months ago
Combining sequence-based prediction methods and circular dichroism and infrared spectroscopic data to improve protein secondary
Background: A number of sequence-based methods exist for protein secondary structure prediction. Protein secondary structures can also be determined experimentally from circular d...
Jonathan G. Lees, Robert W. Janes
BMCBI
2006
131views more  BMCBI 2006»
14 years 11 months ago
Statistical modeling of biomedical corpora: mining the Caenorhabditis Genetic Center Bibliography for genes related to life span
Background: The statistical modeling of biomedical corpora could yield integrated, coarse-to-fine views of biological phenomena that complement discoveries made from analysis of m...
David M. Blei, K. Franks, Michael I. Jordan, I. Sa...
IVS
2007
110views more  IVS 2007»
14 years 11 months ago
An automated approach for the optimization of pixel-based visualizations
During the last two decades, a wide variety of advanced methods for the visual exploration of large data sets have been proposed. For most of these techniques user interaction has...
Jörn Schneidewind, Mike Sips, Daniel A. Keim
BMCBI
2004
136views more  BMCBI 2004»
14 years 11 months ago
A SNP-centric database for the investigation of the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are an increasingly important tool for genetic and biomedical research. Although current genomic databases contain information o...
Alberto Riva, Isaac S. Kohane