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» A Greedy Algorithm for Aligning DNA Sequences
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BMEI
2008
IEEE
15 years 3 months ago
A New Approach for Tree Alignment Based on Local Re-Optimization
Multiple sequence alignment is the most fundamental task in bioinformatics and computational biology. In this paper, we present a new algorithm to conduct multiple sequences align...
Feng Yue, Jijun Tang
BIBM
2009
IEEE
118views Bioinformatics» more  BIBM 2009»
15 years 1 months ago
Inexact Local Alignment Search over Suffix Arrays
We describe an algorithm for finding approximate seeds for DNA homology searches. In contrast to previous algorithms that use exact or spaced seeds, our approximate seeds may conta...
Mohammadreza Ghodsi, Mihai Pop
BMCBI
2007
233views more  BMCBI 2007»
14 years 9 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong
AAAI
2000
14 years 10 months ago
Divide-and-Conquer Frontier Search Applied to Optimal Sequence Alignment
We present a new algorithm that reduces the space complexity of heuristic search. It is most effective for problem spaces that grow polynomially with problem size, but contain lar...
Richard E. Korf, Weixiong Zhang
IPPS
2003
IEEE
15 years 2 months ago
Sequence Alignment on the Cray MTA-2
The standard algorithm for alignment of DNA sequences using dynamic programming has been implemented on the Cray MTA-2 (Multithreaded Architecture-2) at ENRI (Electronic Navigatio...
Shahid H. Bokhari, Jon R. Sauer