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95
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BMCBI
2010
150views more  BMCBI 2010»
14 years 12 months ago
Evolutionary rates at codon sites may be used to align sequences and infer protein domain function
Background: Sequence alignments form part of many investigations in molecular biology, including the determination of phylogenetic relationships, the prediction of protein structu...
Pierre M. Durand, Scott Hazelhurst, Theresa L. Coe...
96
Voted
GCB
2003
Springer
164views Biometrics» more  GCB 2003»
15 years 5 months ago
Integrative machine learning approach for multi-class SCOP protein fold classification
: Classification and prediction of protein structure has been a central research theme in structural bioinformatics. Due to the imbalanced distribution of proteins over multi SCOP ...
Aik Choon Tan, David Gilbert, Yves Deville
ICANNGA
2007
Springer
112views Algorithms» more  ICANNGA 2007»
15 years 5 months ago
Multiple Sequence Alignment with Evolutionary-Progressive Method
A new evolutionary-progressive method for Multiple Sequence Alignment problem is proposed. The method efficiently combines flexibility of evolutionary approach with speed and accu...
Pawel Kupis, Jacek Mandziuk
BIOSYSTEMS
2010
82views more  BIOSYSTEMS 2010»
14 years 12 months ago
A rate distortion approach to protein symmetry
A spontaneous symmetry breaking argument is applied to the problem of protein form, via a Rate Distortion analysis of the relation between genome coding and the final condensation...
Rodrick Wallace
BMCBI
2008
170views more  BMCBI 2008»
14 years 12 months ago
A genetic approach for building different alphabets for peptide and protein classification
Background: In this paper, it is proposed an optimization approach for producing reduced alphabets for peptide classification, using a Genetic Algorithm. The classification task i...
Loris Nanni, Alessandra Lumini