Sciweavers

225 search results - page 27 / 45
» A Hybrid Evolutionary Approach for the Protein Classificatio...
Sort
View
BMCBI
2010
156views more  BMCBI 2010»
14 years 12 months ago
Comparative classification of species and the study of pathway evolution based on the alignment of metabolic pathways
Background: Pathways provide topical descriptions of cellular circuitry. Comparing analogous pathways reveals intricate insights into individual functional differences among speci...
Adi Mano, Tamir Tuller, Oded Béjà, R...
EVOW
2009
Springer
15 years 6 months ago
Validation of a Morphogenesis Model of Drosophila Early Development by a Multi-objective Evolutionary Optimization Algorithm
We apply evolutionary computation to calibrate the parameters of a morphogenesis model of Drosophila early development. The model aims to describe the establishment of the steady g...
Rui Dilão, Daniele Muraro, Miguel Nicolau, ...
RECOMB
2009
Springer
15 years 6 months ago
Protein Fragment Swapping: A Method for Asymmetric, Selective Site-Directed Recombination
This paper presents a new approach to site-directed recombination, swapping combinations of selected discontiguous fragments from a source protein in place of corresponding fragmen...
Wei Zheng, Karl E. Griswold, Chris Bailey-Kellogg
BMCBI
2010
139views more  BMCBI 2010»
14 years 12 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
SYNASC
2006
IEEE
95views Algorithms» more  SYNASC 2006»
15 years 5 months ago
Evolutionary Support Vector Regression Machines
Evolutionary support vector machines (ESVMs) are a novel technique that assimilates the learning engine of the state-of-the-art support vector machines (SVMs) but evolves the coef...
Ruxandra Stoean, Dumitru Dumitrescu, Mike Preuss, ...