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CMSB
2009
Springer
15 years 1 months ago
On Coupling Models Using Model-Checking: Effects of Irinotecan Injections on the Mammalian Cell Cycle
Abstract. In systems biology, the number of models of cellular processes increases rapidly, but re-using models in different contexts or for different questions remains a challengi...
Elisabetta De Maria, François Fages, Sylvai...
BIOINFORMATICS
2007
83views more  BIOINFORMATICS 2007»
14 years 9 months ago
Exploring biological network structure using exponential random graph models
Motivation: The functioning of biological networks depends in large part on their complex underlying structure. When studying their systemic nature many modeling approaches focus ...
Zachary M. Saul, Vladimir Filkov
ESWA
2006
103views more  ESWA 2006»
14 years 9 months ago
Model gene network by semi-fixed Bayesian network
Gene networks describe functional pathways in a given cell or tissue, representing processes such as metabolism, gene expression regulation, and protein or RNA transport. Thus, le...
Tie-Fei Liu, Wing-Kin Sung, Ankush Mittal
80
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APBC
2004
122views Bioinformatics» more  APBC 2004»
14 years 11 months ago
Integrating Biopathway Databases for Large-scale Modeling and Simulation
Biopathway databases have been developed, such as KEGG and EcoCyc, that compile interaction structures of biopathways together with biological annotations. However, these biopathw...
Masao Nagasaki, Atsushi Doi, Hiroshi Matsuno, Sato...
CPAIOR
2008
Springer
14 years 11 months ago
Connections in Networks: A Hybrid Approach
This paper extends our previous work by exploring the use of a hybrid solution method for solving the connection subgraph problem. We employ a two phase solution method, which dras...
Carla P. Gomes, Willem Jan van Hoeve, Ashish Sabha...