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RECOMB
2010
Springer
14 years 11 months ago
Algorithms for Detecting Significantly Mutated Pathways in Cancer
Abstract. Recent genome sequencing studies have shown that the somatic mutations that drive cancer development are distributed across a large number of genes. This mutational heter...
Fabio Vandin, Eli Upfal, Benjamin J. Raphael
BMCBI
2008
179views more  BMCBI 2008»
14 years 9 months ago
Improving the power for detecting overlapping genes from multiple DNA microarray-derived gene lists
Background: In DNA microarray gene expression profiling studies, a fundamental task is to extract statistically significant genes that meet certain research hypothesis. Currently,...
Xutao Deng, Jun Xu, Charles Wang
BMCBI
2008
133views more  BMCBI 2008»
14 years 9 months ago
CORE_TF: a user-friendly interface to identify evolutionary conserved transcription factor binding sites in sets of co-regulated
Background: The identification of transcription factor binding sites is difficult since they are only a small number of nucleotides in size, resulting in large numbers of false po...
Matthew S. Hestand, Michiel van Galen, Michel P. V...