Background: The rapid development of structural genomics has resulted in many "unknown function" proteins being deposited in Protein Data Bank (PDB), thus, the functiona...
This paper presents an enhanced genetic algorithm for the protein structure prediction problem. A new fitness function, that uses the concept of radius of gyration, is proposed. Al...
Background: Knowledge-based potentials have been widely used in the last 20 years for fold recognition, protein structure prediction from amino acid sequence, ligand binding, prot...
Yaping Feng, Andrzej Kloczkowski, Robert L. Jernig...
Background: Protein alignments are an essential tool for many bioinformatics analyses. While sequence alignments are accurate for proteins of high sequence similarity, they become...
Florian Teichert, Jonas Minning, Ugo Bastolla, Mar...
We carry out a comprehensive study of long-range interactions on a large data set of non-homologous proteins. Our study reveals that the long-range interactions between amino acid...