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JBCB
2010
138views more  JBCB 2010»
14 years 8 months ago
Hierarchical Classification of Gene Ontology Terms Using the Gostruct Method
Protein function prediction is an active area of research in bioinformatics. And yet, transfer of annotation on the basis of sequence or structural similarity remains widely used ...
Artem Sokolov, Asa Ben-Hur
CIBCB
2009
IEEE
15 years 2 months ago
DDPIn - Distance and density based protein indexing
Protein structure similarity and classification methods have many applications in protein function prediction and associated fields (e.g. drug discovery). In this paper, we propose...
David Hoksza
BMCBI
2008
116views more  BMCBI 2008»
15 years 1 months ago
Impact of residue accessible surface area on the prediction of protein secondary structures
Background: The problem of accurate prediction of protein secondary structure continues to be one of the challenging problems in Bioinformatics. It has been previously suggested t...
Amir Momen-Roknabadi, Mehdi Sadeghi, Hamid Pezeshk...
BMCBI
2008
137views more  BMCBI 2008»
15 years 1 months ago
A dynamic Bayesian network approach to protein secondary structure prediction
Background: Protein secondary structure prediction method based on probabilistic models such as hidden Markov model (HMM) appeals to many because it provides meaningful informatio...
Xin-Qiu Yao, Huaiqiu Zhu, Zhen-Su She
GCB
2005
Springer
117views Biometrics» more  GCB 2005»
15 years 7 months ago
Generation of 3D templates of active sites of proteins with rigid prosthetic groups
Motivation: With the increasing availability of protein structures, the generation of biologically meaningful 3D patterns from the simultaneous alignment of several protein struct...
Jean-Christophe Nebel