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ICML
2005
IEEE
16 years 2 months ago
Predicting protein folds with structural repeats using a chain graph model
Protein fold recognition is a key step towards inferring the tertiary structures from amino-acid sequences. Complex folds such as those consisting of interacting structural repeat...
Yan Liu, Eric P. Xing, Jaime G. Carbonell
GECCO
2008
Springer
164views Optimization» more  GECCO 2008»
15 years 2 months ago
Genetic algorithms with local search optimization for protein structure prediction problem
This paper presents a new Genetic Algorithm for Protein Structure Prediction problem in both 2D and 3D hydrophobichydrophilic lattice models, introduced in [1]. Our algorithm evol...
Igor Berenboym, Mireille Avigal
BMCBI
2006
129views more  BMCBI 2006»
15 years 1 months ago
Improved alignment quality by combining evolutionary information, predicted secondary structure and self-organizing maps
Background: Protein sequence alignment is one of the basic tools in bioinformatics. Correct alignments are required for a range of tasks including the derivation of phylogenetic t...
Tomas Ohlson, Varun Aggarwal, Arne Elofsson, Rober...
BMCBI
2006
101views more  BMCBI 2006»
15 years 1 months ago
Predicting residue contacts using pragmatic correlated mutations method: reducing the false positives
Background: Predicting residues' contacts using primary amino acid sequence alone is an important task that can guide 3D structure modeling and can verify the quality of the ...
Petras J. Kundrotas, Emil Alexov
JCB
2000
146views more  JCB 2000»
15 years 1 months ago
Bayesian Segmentation of Protein Secondary Structure
We present a novel method for predicting the secondary structure of a protein from its amino acid sequence. Most existing methods predict each position in turn based on a local wi...
Scott C. Schmidler, Jun S. Liu, Douglas L. Brutlag