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LION
2009
Springer
135views Optimization» more  LION 2009»
15 years 8 months ago
Neural Network Pairwise Interaction Fields for Protein Model Quality Assessment
We present a new knowledge-based Model Quality Assessment Program (MQAP) at the residue level which evaluates single protein structure models. We use a tree representation of the ...
Alberto J. M. Martin, Alessandro Vullo, Gianluca P...
CSB
2005
IEEE
143views Bioinformatics» more  CSB 2005»
15 years 7 months ago
Analysis of four different sets of predictive features for metalloproteins
Metals bound to the protein are important for functional or structural roles. Despite their importance there is a distinct lack of research for identification of metalloproteins f...
Huseyin Seker, Parvez I. Haris
NAR
2008
152views more  NAR 2008»
15 years 1 months ago
PROMALS3D web server for accurate multiple protein sequence and structure alignments
Multiple sequence alignments are essential in computational sequence and structural analysis, with applications in homology detection, structure modeling, function prediction and ...
Jimin Pei, Ming Tang, Nick V. Grishin
BMCBI
2006
118views more  BMCBI 2006»
15 years 1 months ago
Predicting the effect of missense mutations on protein function: analysis with Bayesian networks
Background: A number of methods that use both protein structural and evolutionary information are available to predict the functional consequences of missense mutations. However, ...
Chris J. Needham, James R. Bradford, Andrew J. Bul...
BMCBI
2010
123views more  BMCBI 2010»
15 years 1 months ago
A new protein binding pocket similarity measure based on comparison of clouds of atoms in 3D: application to ligand prediction
Background: Predicting which molecules can bind to a given binding site of a protein with known 3D structure is important to decipher the protein function, and useful in drug desi...
Brice Hoffmann, Mikhail Zaslavskiy, Jean-Philippe ...