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BMCBI
2008
112views more  BMCBI 2008»
15 years 1 months ago
Predicting the Interactome of Xanthomonas oryzae pathovar oryzae for target selection and DB service
Background: Protein-protein interactions (PPIs) play key roles in various cellular functions. In addition, some critical inter-species interactions such as host-pathogen interacti...
Jeong-Gu Kim, Daeui Park, Byoung-Chul Kim, Seong-W...
PAKDD
2005
ACM
180views Data Mining» more  PAKDD 2005»
15 years 7 months ago
Conditional Random Fields for Transmembrane Helix Prediction
Abstract. It is estimated that 20% of genes in the human genome encode for integral membrane proteins (IMPs) and some estimates are much higher. IMPs control a broad range of event...
Lior Lukov, Sanjay Chawla, W. Bret Church
NIPS
2004
15 years 3 months ago
Identifying Protein-Protein Interaction Sites on a Genome-Wide Scale
Protein interactions typically arise from a physical interaction of one or more small sites on the surface of the two proteins. Identifying these sites is very important for drug ...
Haidong Wang, Eran Segal, Asa Ben-Hur, Daphne Koll...
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BMCBI
2007
144views more  BMCBI 2007»
15 years 1 months ago
Motif kernel generated by genetic programming improves remote homology and fold detection
Background: Protein remote homology detection is a central problem in computational biology. Most recent methods train support vector machines to discriminate between related and ...
Tony Håndstad, Arne J. H. Hestnes, Pål...
BMCBI
2005
118views more  BMCBI 2005»
15 years 1 months ago
Variation in structural location and amino acid conservation of functional sites in protein domain families
Background: The functional sites of a protein present important information for determining its cellular function and are fundamental in drug design. Accordingly, accurate methods...
Birgit Pils, Richard R. Copley, Jörg Schultz