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BMCBI
2010
131views more  BMCBI 2010»
14 years 8 months ago
Dynamics based alignment of proteins: an alternative approach to quantify dynamic similarity
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
Márton Münz, Rune B. Lyngsø, Jo...
BMCBI
2007
97views more  BMCBI 2007»
15 years 1 months ago
Relating destabilizing regions to known functional sites in proteins
Background: Most methods for predicting functional sites in protein 3D structures, rely on information on related proteins and cannot be applied to proteins with no known relative...
Benoit H. Dessailly, Marc F. Lensink, Shoshana J. ...
BMCBI
2008
114views more  BMCBI 2008»
15 years 1 months ago
Combining classifiers for improved classification of proteins from sequence or structure
Background: Predicting a protein's structural or functional class from its amino acid sequence or structure is a fundamental problem in computational biology. Recently, there...
Iain Melvin, Jason Weston, Christina S. Leslie, Wi...
BMCBI
2006
152views more  BMCBI 2006»
15 years 1 months ago
Predicting deleterious nsSNPs: an analysis of sequence and structural attributes
Background: There has been an explosion in the number of single nucleotide polymorphisms (SNPs) within public databases. In this study we focused on non-synonymous protein coding ...
Richard J. B. Dobson, Patricia B. Munroe, Mark J. ...
IJCBDD
2010
127views more  IJCBDD 2010»
15 years 6 days ago
Predicting protein complexes by data integration of different types of interactions
: The explosion of highthroughput interaction data from proteomics studies gives us the opportunity to integrate Protein-Protein Interactions (PPI) from different type of interacti...
Powell Patrick Cheng Tan, Daryanaz Dargahi, Freder...