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BMCBI
2008
147views more  BMCBI 2008»
15 years 1 months ago
Transmembrane helix prediction using amino acid property features and latent semantic analysis
Background: Prediction of transmembrane (TM) helices by statistical methods suffers from lack of sufficient training data. Current best methods use hundreds or even thousands of f...
Madhavi Ganapathiraju, Narayanas Balakrishnan, Raj...
NIPS
2004
15 years 3 months ago
Large-Scale Prediction of Disulphide Bond Connectivity
The formation of disulphide bridges among cysteines is an important feature of protein structures. Here we develop new methods for the prediction of disulphide bond connectivity. ...
Pierre Baldi, Jianlin Cheng, Alessandro Vullo
BMCBI
2010
118views more  BMCBI 2010»
15 years 1 months ago
Computing H/D-Exchange rates of single residues from data of proteolytic fragments
Background: Protein conformation and protein/protein interaction can be elucidated by solution-phase Hydrogen/ Deuterium exchange (sHDX) coupled to high-resolution mass analysis o...
Ernst Althaus, Stefan Canzar, Carsten Ehrler, Mark...
BMCBI
2007
128views more  BMCBI 2007»
15 years 1 months ago
Detailed estimation of bioinformatics prediction reliability through the Fragmented Prediction Performance Plots
Background: An important and yet rather neglected question related to bioinformatics predictions is the estimation of the amount of data that is needed to allow reliable predictio...
Oliviero Carugo
JCB
2000
90views more  JCB 2000»
15 years 1 months ago
Geometric Invariant Core for the CL and CH1 Domains of Immunoglobulin Molecules
A previously developed algorithmic method for identifying a geometric invariant of protein structures, termed geometrical core, is extended to the and 1 domains of immunoglobulin ...
Ognyan Stoyanov, Alexander Kister, Israel Gelfand,...