385 search results - page 45 / 77 » A Knowledge-Based Method for Protein Structure Refinement an... |
111
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BMCBI
2010
15 years 1 months ago
2010
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
123
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BMCBI
2004
15 years 1 months ago
2004
Background: Accessible surface area (ASA) or solvent accessibility of amino acids in a protein has important implications. Knowledge of surface residues helps in locating potentia...
129
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BMCBI
2010
15 years 1 months ago
2010
Background: Natively unfolded proteins lack a well defined three dimensional structure but have important biological functions, suggesting a re-assignment of the structure-functio...
106
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BMCBI
2007
15 years 1 months ago
2007
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
102
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APBC
2004
15 years 3 months ago
2004
Transcription factors play essential role in the gene regulation in higher organisms, binding to multiple target sequences and regulating multiple genes in a complex manner. In or...