Background: In order to improve gene prediction, extrinsic evidence on the gene structure can be collected from various sources of information such as genome-genome comparisons an...
Background: Since many of the new protein structures delivered by high-throughput processes do not have any known function, there is a need for structure-based prediction of prote...
Jean-Christophe Nebel, Pawel Herzyk, David R. Gilb...
Background: More and more disordered regions have been discovered in protein sequences, and many of them are found to be functionally significant. Previous studies reveal that dis...
Background: Ab initio protein structure prediction methods generate numerous structural candidates, which are referred to as decoys. The decoy with the most number of neighbors of...
Background: Genome-wide association studies of common diseases for common, low penetrance causal variants are underway. A proportion of these will alter protein sequences, the mos...
David F. Burke, Catherine L. Worth, Eva-Maria Prie...