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CORR
2010
Springer
144views Education» more  CORR 2010»
14 years 11 months ago
CLP-based protein fragment assembly
Abstract. The paper investigates a novel approach, based on Constraint Logic Programming (CLP), to predict the 3D conformation of a protein via fragments assembly. The fragments ar...
Alessandro Dal Palù, Agostino Dovier, Feder...
BMCBI
2010
112views more  BMCBI 2010»
14 years 12 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
86
Voted
COCOON
2009
Springer
15 years 6 months ago
Determination of Glycan Structure from Tandem Mass Spectra
Glycans are molecules made from simple sugars that form complex tree structures. Glycans constitute one of the most important protein modifications, and identification of glycans...
Sebastian Böcker, Birte Kehr, Florian Rasche
CONSTRAINTS
2008
182views more  CONSTRAINTS 2008»
14 years 11 months ago
Constraint Programming in Structural Bioinformatics
Bioinformatics aims at applying computer science methods to the wealth of data collected in a variety of experiments in life sciences (e.g. cell and molecular biology, biochemistry...
Pedro Barahona, Ludwig Krippahl
77
Voted
BMCBI
2006
137views more  BMCBI 2006»
14 years 11 months ago
A maximum likelihood framework for protein design
Background: The aim of protein design is to predict amino-acid sequences compatible with a given target structure. Traditionally envisioned as a purely thermodynamic question, thi...
Claudia L. Kleinman, Nicolas Rodrigue, Céci...