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BMCBI
2004
196views more  BMCBI 2004»
14 years 11 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
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BMCBI
2006
108views more  BMCBI 2006»
14 years 11 months ago
NOXclass: prediction of protein-protein interaction types
Background: Structural models determined by X-ray crystallography play a central role in understanding protein-protein interactions at the molecular level. Interpretation of these...
Hongbo Zhu, Francisco S. Domingues, Ingolf Sommer,...
BMCBI
2004
96views more  BMCBI 2004»
14 years 11 months ago
A hybrid clustering approach to recognition of protein families in 114 microbial genomes
Background: Grouping proteins into sequence-based clusters is a fundamental step in many bioinformatic analyses (e.g., homology-based prediction of structure or function). Standar...
Timothy J. Harlow, J. Peter Gogarten, Mark A. Raga...
BMCBI
2010
95views more  BMCBI 2010»
14 years 11 months ago
EPSVR and EPMeta: prediction of antigenic epitopes using support vector regression and multiple server results
Background: Accurate prediction of antigenic epitopes is important for immunologic research and medical applications, but it is still an open problem in bioinformatics. The case f...
Shide Liang, Dandan Zheng, Daron M. Standley, Bo Y...
BMCBI
2010
147views more  BMCBI 2010»
14 years 11 months ago
Learning biological network using mutual information and conditional independence
Background: Biological networks offer us a new way to investigate the interactions among different components and address the biological system as a whole. In this paper, a revers...
Dong-Chul Kim, Xiaoyu Wang, Chin-Rang Yang, Jean G...