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ACRI
2008
Springer
15 years 3 months ago
Automatic Design of FPGA Processor for the Backtracking of DNA Sequences Evolution Using Cellular Automata and Genetic Algorithm
In several cases, the DNA sequences of an organism are available in different stages of its evolution and it is desirable to reconstruct the DNA sequence in a previous evolution st...
Georgios Ch. Sirakoulis
71
Voted
HYBRID
2007
Springer
15 years 3 months ago
Switch Detection in Genetic Regulatory Networks
Abstract. This paper considers piecewise affine models of genetic regulatory networks and focuses on the problem of detecting switches among different modes of operation in gene e...
Riccardo Porreca, Giancarlo Ferrari-Trecate, Danie...
76
Voted
STOC
2006
ACM
129views Algorithms» more  STOC 2006»
15 years 9 months ago
Optimal phylogenetic reconstruction
One of the major tasks of evolutionary biology is the reconstruction of phylogenetic trees from molecular data. The evolutionary model is given by a Markov chain on the true evolu...
Constantinos Daskalakis, Elchanan Mossel, Sé...
RECOMB
2003
Springer
15 years 9 months ago
Large scale reconstruction of haplotypes from genotype data
Critical to the understanding of the genetic basis for complex diseases is the modeling of human variation. Most of this variation can be characterized by single nucleotide polymo...
Eleazar Eskin, Eran Halperin, Richard M. Karp
NN
2007
Springer
267views Neural Networks» more  NN 2007»
14 years 9 months ago
Modeling of gene regulatory networks with hybrid differential evolution and particle swarm optimization
In the last decade, recurrent neural networks (RNNs) have attracted more efforts in inferring genetic regulatory networks (GRNs), using time series gene expression data from micro...
Rui Xu, Ganesh K. Venayagamoorthy, Donald C. Wunsc...