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CEC
2008
IEEE
15 years 3 months ago
A self-adaptive cellular memetic algorithm for the DNA fragment assembly problem
Abstract— The DNA fragment assembly problem is to reconstruct a DNA chain from multiple fragments that have previously been sequenced in a laboratory. This is a critical step in ...
Bernabé Dorronsoro, Enrique Alba, Gabriel L...
72
Voted
GECCO
2007
Springer
131views Optimization» more  GECCO 2007»
15 years 3 months ago
Using feedback to regulate gene expression in a developmental control architecture
We present what we believe is the first attempt to physically reconstruct the exploratory mechanism of genetic regulatory networks. Feedback plays a crucial role during developme...
Kester Clegg, Susan Stepney, Tim Clarke
95
Voted
BIOCOMP
2009
14 years 10 months ago
Inferring Gene Regulatory Networks from Asynchronous Microarray Data
Modern approaches to treating genetic disorders, cancers and even epidemics rely on a detailed understanding of the underlying gene signaling network. Previous work has used time s...
David Oviatt, Mark J. Clement, Quinn Snell, Kennet...
TCBB
2008
107views more  TCBB 2008»
14 years 9 months ago
Progressive Tree Neighborhood Applied to the Maximum Parsimony Problem
Abstract-- The Maximum Parsimony problem aims at reconstructing a phylogenetic tree from DNA sequences while minimizing the number of genetic transformations. To solve this NP-comp...
Adrien Goëffon, Jean-Michel Richer, Jin-Kao H...
RECOMB
2010
Springer
15 years 4 months ago
On the Genealogy of Asexual Diploids
Given molecular genetic data from diploid individuals that, at present, reproduce mostly or exclusively asexually without recombination, an important problem in evolutionary biolog...
Fumei Lam, Charles H. Langley, Yun S. Song