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» A Method of Requirement Inconsistency Analysis
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BMCBI
2010
208views more  BMCBI 2010»
14 years 10 months ago
Using machine learning to speed up manual image annotation: application to a 3D imaging protocol for measuring single cell gene
Background: Image analysis is an essential component in many biological experiments that study gene expression, cell cycle progression, and protein localization. A protocol for tr...
Zafer Aydin, John I. Murray, Robert H. Waterston, ...
BMCBI
2007
128views more  BMCBI 2007»
14 years 10 months ago
A robust and efficient algorithm for the shape description of protein structures and its application in predicting ligand bindin
Background: An accurate description of protein shape derived from protein structure is necessary to establish an understanding of protein-ligand interactions, which in turn will l...
Lei Xie, Philip E. Bourne
BMCBI
2005
124views more  BMCBI 2005»
14 years 10 months ago
Tools enabling the elucidation of molecular pathways active in human disease: Application to Hepatitis C virus infection
Background: The extraction of biological knowledge from genome-scale data sets requires its analysis in the context of additional biological information. The importance of integra...
David J. Reiss, Iliana Avila-Campillo, Vesteinn Th...
BMCBI
2004
228views more  BMCBI 2004»
14 years 9 months ago
An XML standard for the dissemination of annotated 2D gel electrophoresis data complemented with mass spectrometry results
Background: Many proteomics initiatives require a seamless bioinformatics integration of a range of analytical steps between sample collection and systems modeling immediately ass...
Romesh Stanislaus, Liu Hong Jiang, Martha Swartz, ...
CSUR
1999
159views more  CSUR 1999»
14 years 9 months ago
Hubs, authorities, and communities
The Web can be naturally modeled as a directed graph, consisting of a set of abstract nodes (the pages) joined by directional edges (the hyperlinks). Hyperlinks encode a considerab...
Jon M. Kleinberg