It is not always clear how best to represent integrated data sets, and which application and database features allow a scientist to take best advantage of data coming from various ...
Joanna Jakubowska, Ela Hunt, John McClure, Matthew...
Abstract. There is widespread interest in comparative genomics in determining if historically and/or functionally related genes are spatially clustered in the genome, and whether t...
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
Background: Identification of RNA homologs within genomic stretches is difficult when pairwise sequence identity is low or unalignable flanking residues are present. In both cases...
Usman Roshan, Satish Chikkagoudar, Dennis R. Lives...