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» A Methodology for Comparative Functional Genomics
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DILS
2008
Springer
14 years 11 months ago
VisGenome and Ensembl: Usability of Integrated Genome Maps
It is not always clear how best to represent integrated data sets, and which application and database features allow a scientist to take best advantage of data coming from various ...
Joanna Jakubowska, Ela Hunt, John McClure, Matthew...
75
Voted
RECOMB
2005
Springer
15 years 10 months ago
The Incompatible Desiderata of Gene Cluster Properties
Abstract. There is widespread interest in comparative genomics in determining if historically and/or functionally related genes are spatially clustered in the genome, and whether t...
Rose Hoberman, Dannie Durand
BMCBI
2007
106views more  BMCBI 2007»
14 years 9 months ago
Discovering functional linkages and uncharacterized cellular pathways using phylogenetic profile comparisons: a comprehensive as
Background: A widely-used approach for discovering functional and physical interactions among proteins involves phylogenetic profile comparisons (PPCs). Here, proteins with simila...
Raja Jothi, Teresa M. Przytycka, L. Aravind
108
Voted
BMCBI
2004
144views more  BMCBI 2004»
14 years 9 months ago
GOtcha: a new method for prediction of protein function assessed by the annotation of seven genomes
Background: The function of a novel gene product is typically predicted by transitive assignment of annotation from similar sequences. We describe a novel method, GOtcha, for pred...
David M. A. Martin, Matthew Berriman, Geoffrey J. ...
BMCBI
2008
106views more  BMCBI 2008»
14 years 9 months ago
Searching for evolutionary distant RNA homologs within genomic sequences using partition function posterior probabilities
Background: Identification of RNA homologs within genomic stretches is difficult when pairwise sequence identity is low or unalignable flanking residues are present. In both cases...
Usman Roshan, Satish Chikkagoudar, Dennis R. Lives...