Background: Sequencing metagenomes that were pre-amplified with primer-based methods requires the removal of the additional tag sequences from the datasets. The sequenced reads ca...
Robert Schmieder, Yan Wei Lim, Forest Rohwer, Robe...
Abstract. Motivation: Although studies have shown that genetic alterations are causally involved in numerous human diseases, still not much is known about the molecular mechanisms ...
Anneleen Daemen, Olivier Gevaert, Karin Leunen, Va...
Background: Automated comparison of complete sets of genes encoded in two genomes can provide insight on the genetic basis of differences in biological traits between species. Gen...
Overlapping genes (encoded on the same DNA strand but in different frames) are thought to be rare and, therefore, were largely neglected in the past. In a test set of 800 viruses ...
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...