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» A Methodology for Comparative Functional Genomics
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BMCBI
2010
107views more  BMCBI 2010»
14 years 9 months ago
TagCleaner: Identification and removal of tag sequences from genomic and metagenomic datasets
Background: Sequencing metagenomes that were pre-amplified with primer-based methods requires the removal of the additional tag sequences from the datasets. The sequenced reads ca...
Robert Schmieder, Yan Wei Lim, Forest Rohwer, Robe...
KES
2008
Springer
14 years 8 months ago
Classification of Sporadic and BRCA1 Ovarian Cancer Based on a Genome-Wide Study of Copy Number Variations
Abstract. Motivation: Although studies have shown that genetic alterations are causally involved in numerous human diseases, still not much is known about the molecular mechanisms ...
Anneleen Daemen, Olivier Gevaert, Karin Leunen, Va...
BMCBI
2006
122views more  BMCBI 2006»
14 years 9 months ago
Genome comparison using Gene Ontology (GO) with statistical testing
Background: Automated comparison of complete sets of genes encoded in two genomes can provide insight on the genetic basis of differences in biological traits between species. Gen...
Zhaotao Cai, Xizeng Mao, Songgang Li, Liping Wei
EVOW
2010
Springer
15 years 4 months ago
Towards Automatic Detecting of Overlapping Genes - Clustered BLAST Analysis of Viral Genomes
Overlapping genes (encoded on the same DNA strand but in different frames) are thought to be rare and, therefore, were largely neglected in the past. In a test set of 800 viruses ...
Klaus Neuhaus, Daniela Oelke, David Fürst, Si...
BMCBI
2006
126views more  BMCBI 2006»
14 years 9 months ago
A Regression-based K nearest neighbor algorithm for gene function prediction from heterogeneous data
Background: As a variety of functional genomic and proteomic techniques become available, there is an increasing need for functional analysis methodologies that integrate heteroge...
Zizhen Yao, Walter L. Ruzzo