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» A Methodology for Comparative Functional Genomics
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BMCBI
2010
101views more  BMCBI 2010»
14 years 9 months ago
Comparative analysis of thermophilic and mesophilic proteins using Protein Energy Networks
Background: Thermophilic proteins sustain themselves and function at higher temperatures. Despite their structural and functional similarities with their mesophilic homologues, th...
M. S. Vijayabaskar, Saraswathi Vishveshwara
BMCBI
2004
200views more  BMCBI 2004»
14 years 9 months ago
ABC: software for interactive browsing of genomic multiple sequence alignment data
Background: Alignment and comparison of related genome sequences is a powerful method to identify regions likely to contain functional elements. Such analyses are data intensive, ...
Gregory M. Cooper, Senthil A. G. Singaravelu, Aren...
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BMCBI
2007
100views more  BMCBI 2007»
14 years 9 months ago
PARE: A tool for comparing protein abundance and mRNA expression data
Background: Techniques for measuring protein abundance are rapidly advancing and we are now in a situation where we anticipate many protein abundance data sets will be available i...
Eric Z. Yu, Anne E. Counterman Burba, Mark Gerstei...
BMCBI
2008
152views more  BMCBI 2008»
14 years 9 months ago
JCoast - A biologist-centric software tool for data mining and comparison of prokaryotic (meta)genomes
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...
Michael Richter, Thierry Lombardot, Ivaylo Kostadi...
BIOSURVEILLANCE
2007
Springer
15 years 3 months ago
Detecting Conserved RNA Secondary Structures in Viral Genomes: The RADAR Approach
Abstract. Conserved regions, or motifs, present among RNA secondary structures serve as a useful indicator for predicting the functionality of the RNA molecules. Automated detectio...
Mugdha Khaladkar, Jason T. L. Wang