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» A Methodology for Comparative Functional Genomics
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BMCBI
2006
75views more  BMCBI 2006»
14 years 9 months ago
Improving the specificity of high-throughput ortholog prediction
Background: Orthologs (genes that have diverged after a speciation event) tend to have similar function, and so their prediction has become an important component of comparative g...
Debra L. Fulton, Yvonne Y. Li, Matthew R. Laird, B...
SSDBM
2010
IEEE
220views Database» more  SSDBM 2010»
15 years 2 months ago
Prefix Tree Indexing for Similarity Search and Similarity Joins on Genomic Data
Similarity search and similarity join on strings are important for applications such as duplicate detection, error detection, data cleansing, or comparison of biological sequences....
Astrid Rheinländer, Martin Knobloch, Nicky Ho...
BMCBI
2005
154views more  BMCBI 2005»
14 years 9 months ago
GObar: A Gene Ontology based analysis and visualization tool for gene sets
Background: Microarray experiments, as well as other genomic analyses, often result in large gene sets containing up to several hundred genes. The biological significance of such ...
Jason S. M. Lee, Gurpreet Katari, Ravi Sachidanand...
BMCBI
2008
105views more  BMCBI 2008»
14 years 9 months ago
A gene pattern mining algorithm using interchangeable gene sets for prokaryotes
Background: Mining gene patterns that are common to multiple genomes is an important biological problem, which can lead us to novel biological insights. When family classification...
Meng Hu, Kwangmin Choi, Wei Su, Sun Kim, Jiong Yan...
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NAR
2006
177views more  NAR 2006»
14 years 9 months ago
PUMA2 - grid-based high-throughput analysis of genomes and metabolic pathways
The PUMA2 system (available at http://compbio.mcs. 10 anl.gov/puma2) is an interactive, integrated bioinformatics environment for high-throughput genetic sequence analysis and met...
Natalia Maltsev, Elizabeth M. Glass, Dinanath Sula...