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» A Methodology for Comparative Functional Genomics
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BMCBI
2005
118views more  BMCBI 2005»
14 years 9 months ago
Vestige: Maximum likelihood phylogenetic footprinting
Background: Phylogenetic footprinting is the identification of functional regions of DNA by their evolutionary conservation. This is achieved by comparing orthologous regions from...
Matthew J. Wakefield, Peter Maxwell, Gavin A. Hutt...
BMCBI
2004
158views more  BMCBI 2004»
14 years 9 months ago
Improvement of alignment accuracy utilizing sequentially conserved motifs
Background: Multiple sequence alignment algorithms are very important tools in molecular biology today. Accurate alignment of proteins is central to several areas such as homology...
Saikat Chakrabarti, Nitin Bhardwaj, Prem A. Anand,...
BMCBI
2004
106views more  BMCBI 2004»
14 years 9 months ago
Spotting effect in microarray experiments
Background: Microarray data must be normalized because they suffer from multiple biases. We have identified a source of spatial experimental variability that significantly affects...
Tristan Mary-Huard, Jean-Jacques Daudin, Sté...
BMCBI
2002
131views more  BMCBI 2002»
14 years 9 months ago
Efficient Boolean implementation of universal sequence maps (bUSM)
Background: Recently, Almeida and Vinga offered a new approach for the representation of arbitrary discrete sequences, referred to as Universal Sequence Maps (USM), and discussed ...
John Schwacke, Jonas S. Almeida
BMCBI
2011
14 years 4 months ago
Outer membrane proteins can be simply identified using secondary structure element alignment
Background: Outer membrane proteins (OMPs) are frequently found in the outer membranes of gram-negative bacteria, mitochondria and chloroplasts and have been found to play diverse...
Ren-Xiang Yan, Zhen Chen, Ziding Zhang