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» A Methodology for Comparative Functional Genomics
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BMCBI
2010
122views more  BMCBI 2010»
14 years 9 months ago
Simultaneous prediction of transcription factor binding sites in a group of prokaryotic genomes
Background: Our current understanding of transcription factor binding sites (TFBSs) in sequenced prokaryotic genomes is very limited due to the lack of an accurate and efficient c...
Shaoqiang Zhang, Shan Li, Phuc T. Pham, Zhengchang...
ECAI
2004
Springer
15 years 1 months ago
Avoiding Data Overfitting in Scientific Discovery: Experiments in Functional Genomics
Functional genomics is a typical scientific discovery domain characterized by a very large number of attributes (genes) relative to the number of examples (observations). The dang...
Dragan Gamberger, Nada Lavrac
RECOMB
2002
Springer
15 years 10 months ago
Tests for gene clustering
Comparing chromosomal gene order in two or more related species is an important approach to studying the forces that guide genome organization and evolution. Linked clusters of si...
Dannie Durand, David Sankoff
GECCO
2007
Springer
300views Optimization» more  GECCO 2007»
15 years 3 months ago
Methodology to select solutions from the pareto-optimal set: a comparative study
The resolution of a Multi-Objective Optimization Problem (MOOP) does not end when the Pareto-optimal set is found. In real problems, a single solution must be selected. Ideally, t...
José C. Ferreira, Carlos M. Fonseca, Ant&oa...
DILS
2004
Springer
15 years 3 months ago
Heterogeneous Data Integration with the Consensus Clustering Formalism
Meaningfully integrating massive multi-experimental genomic data sets is becoming critical for the understanding of gene function. We have recently proposed methodologies for integ...
Vladimir Filkov, Steven Skiena