Background: Our current understanding of transcription factor binding sites (TFBSs) in sequenced prokaryotic genomes is very limited due to the lack of an accurate and efficient c...
Shaoqiang Zhang, Shan Li, Phuc T. Pham, Zhengchang...
Functional genomics is a typical scientific discovery domain characterized by a very large number of attributes (genes) relative to the number of examples (observations). The dang...
Comparing chromosomal gene order in two or more related species is an important approach to studying the forces that guide genome organization and evolution. Linked clusters of si...
The resolution of a Multi-Objective Optimization Problem (MOOP) does not end when the Pareto-optimal set is found. In real problems, a single solution must be selected. Ideally, t...
Meaningfully integrating massive multi-experimental genomic data sets is becoming critical for the understanding of gene function. We have recently proposed methodologies for integ...