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BMCBI
2010
86views more  BMCBI 2010»
15 years 4 months ago
A novel approach to simulate gene-environment interactions in complex diseases
Background: Complex diseases are multifactorial traits caused by both genetic and environmental factors. They represent the major part of human diseases and include those with lar...
Roberto Amato, Michele Pinelli, Daniel D'Andrea, G...
BMCBI
2010
154views more  BMCBI 2010»
15 years 4 months ago
Binary image representation of a ligand binding site: its application to efficient sampling of a conformational ensemble
Background: Modelling the ligand binding site of a protein is an important component of understanding proteinligand interactions and is being actively studied. Even if the side ch...
Edon Sung, Sangsoo Kim, Whanchul Shin
BMCBI
2010
143views more  BMCBI 2010»
15 years 4 months ago
An efficient biological pathway layout algorithm combining grid-layout and spring embedder for complicated cellular location inf
Background: Graph drawing is one of the important techniques for understanding biological regulations in a cell or among cells at the pathway level. Among many available layout al...
Kaname Kojima, Masao Nagasaki, Satoru Miyano
BMCBI
2010
137views more  BMCBI 2010»
15 years 4 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
BIOSYSTEMS
2007
90views more  BIOSYSTEMS 2007»
15 years 4 months ago
Directional hearing in a silicon cricket
10 Phonotaxis is the ability to orient towards or away from sound sources. Crickets can locate conspecifics by phonotaxis to the calling (mating) song they produce, and can evade ...
Richard E. Reeve, André van Schaik, Craig T...