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» A Model-Based Approach To Requirements Analysis
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BMCBI
2007
97views more  BMCBI 2007»
14 years 9 months ago
SIRAC: Supervised Identification of Regions of Aberration in aCGH datasets
Background: Array comparative genome hybridization (aCGH) provides information about genomic aberrations. Alterations in the DNA copy number may cause the cell to malfunction, lea...
Carmen Lai, Hugo M. Horlings, Marc J. van de Vijve...
BMCBI
2007
113views more  BMCBI 2007»
14 years 9 months ago
In silico panning for a non-competitive peptide inhibitor
Background: Peptide ligands have tremendous therapeutic potential as efficacious drugs. Currently, more than 40 peptides are available in the market for a drug. However, since cos...
Yukiko Yagi, Kotaro Terada, Takahisa Noma, Kazunor...
BMCBI
2008
218views more  BMCBI 2008»
14 years 9 months ago
LOSITAN: A workbench to detect molecular adaptation based on a Fst-outlier method
Background: Testing for selection is becoming one of the most important steps in the analysis of multilocus population genetics data sets. Existing applications are difficult to u...
Tiago Antao, Ana Lopes, Ricardo J. Lopes, Albano B...
CN
2008
100views more  CN 2008»
14 years 9 months ago
Building resilient low-diameter peer-to-peer topologies
As more applications rely on underlying peer-to-peer topologies, the need for efficient and resilient infrastructure has become more pressing. A number of important classes of top...
Rita H. Wouhaybi, Andrew T. Campbell
COMPUTING
2008
174views more  COMPUTING 2008»
14 years 9 months ago
Multilevel algorithms for Rannacher-Turek finite element approximation of 3D elliptic problems
Generalizing the approach of a previous work [15] the authors present multilevel preconditioners for three-dimensional (3D) elliptic problems discretized by a family of Rannacher ...
Ivan Georgiev, Johannes Kraus, Svetozar Margenov