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» A More Accurate and Efficient Whole Genome Phylogeny
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BMCBI
2010
121views more  BMCBI 2010»
14 years 12 months ago
Reconstructing genome trees of prokaryotes using overlapping genes
Background: Overlapping genes (OGs) are defined as adjacent genes whose coding sequences overlap partially or entirely. In fact, they are ubiquitous in microbial genomes and more ...
Chih-Hsien Cheng, Chung-Han Yang, Hsien-Tai Chiu, ...
RECOMB
2007
Springer
16 years 2 days ago
Improving Inversion Median Computation Using Commuting Reversals and Cycle Information
In the past decade, genome rearrangements have attracted increasing attention from both biologists and computer scientists as a new type of data for phylogenetic analysis. Methods ...
William Arndt, Jijun Tang
BMCBI
2010
126views more  BMCBI 2010»
14 years 12 months ago
Cgaln: fast and space-efficient whole-genome alignment
Background: Whole-genome sequence alignment is an essential process for extracting valuable information about the functions, evolution, and peculiarities of genomes under investig...
Ryuichiro Nakato, Osamu Gotoh
BMCBI
2006
111views more  BMCBI 2006»
14 years 11 months ago
Using ESTs to improve the accuracy of de novo gene prediction
Background: ESTs are a tremendous resource for determining the exon-intron structures of genes, but even extensive EST sequencing tends to leave many exons and genes untouched. Ge...
Chaochun Wei, Michael R. Brent
BMCBI
2008
99views more  BMCBI 2008»
14 years 12 months ago
Multiple organism algorithm for finding ultraconserved elements
Background: Ultraconserved elements are nucleotide or protein sequences with 100% identity (no mismatches, insertions, or deletions) in the same organism or between two or more or...
Scott Christley, Neil F. Lobo, Gregory R. Madey